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imrmc: Size and Analyze Multi-reader Multi-case Reader Studies,     3.1.4 Sizing Future Study

3.1.4 Sizing Future Study

The third panel is for sizing a trial using the components of variance from statistical analysis.
1. Set the number of split-plot groups, pairing of readers, pairing of cases and study size.
2. Set the significance level and the effect size
3. Click “Size a Trial” or "Explore Experiment Size" buttons.
Note: Sizing MLE analysis has not be validated
3.1.4 Sizing Future Study
1

Study Design

1. Study Design
Sets the number of split-plot groups, pairing of readers, pairing of cases.
2

Size MLE Option

2. Size MLE Option
Check box to define whether use Maximum Likelihood Estimate (MLE) in sizing analysis.
3

Significance Setting

3. Significance Setting
 Sets the significance level and the effect size.
4

Study Size

4. Study Size
Sets number of readers, nondiseasedcases, and diseased cases.
5

Size a Trial

5. Size a Trial
Uses components of variance from statistical analysis and sizing parameter to estimate a new MRMC study analysis.
6

Size Multiple Trials

6. Size Multiple Trials
Uses components of variance from statistical analysis to estimate different sizes MRMC studies analyses, and displays results in Explore Experiment Size window.
7

Sizing Results

7. Sizing Results
Normal, BDG and Hills analyses results.

The contents of 3.1.4 Sizing Future Study

3.1.4.1 Explore Experiment Size
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