3.1.4 Sizing Future Study
The third panel is for sizing a trial using the components of variance from statistical analysis.
1. Set the number of split-plot groups, pairing of readers, pairing of cases and study size.
2. Set the significance level and the effect size
3. Click “Size a Trial” or "Explore Experiment Size" buttons.
Note: Sizing MLE analysis has not be validated
 Study Design
Sets the number of split-plot groups, pairing of readers, pairing of cases.
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 Size MLE Option
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 Significance Setting
Sets the significance level and the effect size.
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 Study Size
Sets number of readers, nondiseasedcases, and diseased cases.
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 Size a Trial
Uses components of variance from statistical analysis and sizing parameter to estimate a new MRMC study analysis.
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 Size Multiple Trials
Uses components of variance from statistical analysis to estimate different sizes MRMC studies analyses, and displays results in Explore Experiment Size window.
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 Sizing Results
Normal, BDG and Hills analyses results.
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