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  • 1. Introduction

1. Introduction

iRoeMetz is a Java application that simulates Multi-Reader Multi-Case ROC reader studies. The model for the scores comes from a 1992 paper by Roe and Metz [1] . The application also estimates the total variance of AUC and its variance components [2] and can calculate the true variances and components through numerical integration [3].
 
The simulated experiments (ROC scores) can be saved to validate analysis methods or to explore characteristics of summary statistics (as in sizing a study).
 
For an in-depth explanation of iMRMC/ROC reader studies, refer to section 1 of the iMRMC user guide "Introduction to ROC Reader Studies"(link).
 
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